Glabridin Antioxidant

Category

Cosmetic

Keyword

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Product details

Product Name: Glabridin Antioxidant

Molecular Formula: C₂₀H₂₀O₄
CAS No.: 59870-68-7
Specifications: 20%, 40%, 90%, 98%
Testing Method: HPLC
Activity: Tyrosinase inhibition IC₅₀=0.03μM (Hydroquinone IC₅₀=0.12μM)
Appearance: White, Red-Brown, or Brown-Yellow Powder
Applications: Creams, Masks, Lotions, Sunscreens, etc.
Samples: Free samples available
Packaging: 5kg/bag, 25kg/drum

Nature’s "Brightening Gold"

Glabridin is a flavonoid extracted from the roots of Glycyrrhiza glabra (Licorice). With the molecular formula C₂₀H₂₀O₄, it precisely targets melanin production – earning the title "Surgical Missile of Skin Brightening". Only ~100g of high-purity glabridin can be obtained from 1 ton of licorice roots, making it rarer than gold.

Key Advantages

→ Unmatched Potency:

Tyrosinase inhibition IC₅₀=0.03μM (300% stronger than hydroquinone)

→ Extreme Stability:

Retains >95% activity at 80°C and pH 3-9

→ Molecular Precision:

Benzene ring + isoprenyl side chain docks into tyrosinase’s active site (key-lock fit)

→ Dual-Action Delivery:

Lipophilic: Penetrates stratum corneum

Hydrophilic: Sustained action in dermis

→ Clinical Proof for "glabridin for skin":

12-week human trial: ↓42% melasma area, ↓89% erythema (vs. 17% with arbutin)

Industry-Leading Performance

Parameter	Glabridin	Competitors
Tyrosinase Inhibition	IC₅₀=0.03μM	Hydroquinone: 0.12μM Arbutin: 350μM
Anti-Inflammatory Power	7x stronger than hydrocortisone (J Invest Dermatol)
Photostability	>95% activity after 7 days at 80°C	Vitamin C: 90% loss in 3 days

Solving Industry Pain Points

Application	Competitor Weaknesses	Oasier Solution	Client Benefits
Luxury Serums	377 irritation / VC instability	oasier® N20 (Nano-liposomal)	→ 100% sensitive-skin tolerance → 72% repurchase rate (45 days)
Medical Patches	>30% post-laser rebound pigmentation	oasier® MedPatch (Hydrogel)	→ ↓Rebound rate to 5% → 7-day faster recovery