Effects of tea polyphenols on obesity

In vitro study

By influencing preadipocyte differentiation and proliferation and lowering fat storage, tea polyphenol antioxidants can have an impact on obesity.

For example, investigator Q cultured preadipocytes and intervened with tea polyphenols and theaflavin. The results showed that different concentrations of tea polyphenols and theaflavin inhibited the proliferation, growth, and differentiation of preadipocytes to varying degrees, and the content of triglycerides in cells also decreased.

Investigator Y used black tea as raw material and found through in vitro experiments that the sample could activate pancreatic lipase and inhibit cholesterol esterase, to achieve the effect of lowering blood lipids. Moreover, the polyphenols in the tea base are the main functional components of lowering blood lipids in tea.

 These studies have confirmed the mechanism of tea prevention and control of obesity and also showed that tea polyphenols are the main active substances in tea for weight loss.

Zoopery

Numerous studies have reported that tea polyphenols also exert weight loss effects in animal models.

For example, researchers fed obese rats with different doses of tea polyphenols and found that tea polyphenols were dose-dependent on obese rats.]After different doses of green tea dietary fiber powder in each group for six weeks, it was found that the weight, length, and cholesterol content of each group were decreased, especially in the high-dose group.

The researchers found that tea polyphenols can regulate the expression of adipose tissue in obese rats, and can significantly improve the glucose and lipid metabolism in rats.

The researchers used Pu'er tea extract (PETe) as the research object. After feeding male mice for 15 weeks, they found that the physiological indicators of mice: body weight, liver weight, epididymal and perirenal fat accumulation were significantly reduced. At the same time, both raw PETe and cooked PETe can reduce the obesity of mice induced by high-fat diet.

The above studies confirmed that tea polyphenols can reduce the weight of obese mice, providing an experimental basis and theoretical support for the development of tea weight-loss drugs.

Clinical research

At present, many scholars have used tea polyphenols or tea polyphenols combined with exercise therapy to treat obesity.

Researchers W, design clinical trials, select 50 simple obese adolescent patients randomly divided into two groups, do the same intensity of physical exercise for two months, then take tea polyphenols and placebo(will not cause any impact on the human body, avoid error), the results found that taking tea polyphenols experiment group weight, triglycerides, and cholesterol content decreased significantly, illustrates the significance of tea polyphenols.

Researchers H et al., using a randomized, controlled clinical trial to study the effects of drinking green tea(GT)in overweight and obese women, found that TP treatment for 8 weeks significantly reduced serum low-density lipoprotein(LDL-C), triglycerides(TG)and total cholesterol(TC)levels in overweight women to achieve weight loss.

Researchers X et al., in a randomized controlled trial of 62 obese girls randomly given a placebo or decaffeinated green tea polyphenols extract(DGTP)for three months, the researchers found that BMI and wc decreased significantly in the DGTP group, indicating that DGTP can help reduce the incidence of childhood obesity.

At present, there are few clinical studies on preventing obesity with tea polyphenols alone, but the above clinical studies