L-Ergothioneine antioxidant

Product name: L-Ergothioneine antioxidant
Plant source: Liver fungus 
Spc: 98% 
Appearance: white powder

Test method: HPLC
Physical properties: water-soluble
Web screen pore size: 80 mesh
Uses: Cosmetics
Sample: Free samples are provided
Certification: ISO, KOSHER, Halal, HACCP 
Packaging: 1 kg/aluminum foil bag, 25 kgs/cardboard bucket
Shelf life: 2 years, except for no special instructions
Storage precautions: sealed shading, stored in a dry, cool environment

What is L-Ergothionein
L-Ergothionein is a natural antioxidant, that can protect the cells in the human body, and is an important active substance in the body. Natural antioxidants are safe, and non-toxic, and have become research hotspots. L-Ergothionein antioxidant has been widely used in the cosmetics industry. It has many physiological functions, such as scavenging free radicals, detoxification, maintaining DNA biosynthesis, normal growth of cells, and cellular immunity.

Range of L-Ergothionein antioxidant
L-Ergothionein is distributed in some tissues and organs of mammals, mainly in red blood cells (about 1~2 mmol.L) and the semen of some animals. Although there is no experimental study to show that animals can synthesize this substance, there must be ways to absorb and retain ergothiine in animal cells.
The precursor histidine trimethyl internal salt (heroine) can be produced in the edible fungi, mushrooms, and umbrella, and rare amino acids such as ergotamine.

Antioxygenation
L-Ergothionein antioxidant is a kind of natural amino acid from plants, and can accumulate in animals, studies prove that it has the effect of an antioxidant, it can effectively remove-OH, can chelate bivalent iron ions and copper ion, prevent H2O2 under the action of iron ion or copper ion-OH, also can inhibit copper ion-dependent type of oxyhemoglobin oxidation can also inhibit in myoglobin (or hemoglobin) and H2O2 mixed arachidonic acid. Ergothionine also strongly removes hypochlorous acid, thereby preventing the inactivation of A 1-antiprotease. However, it cannot inhibit the peroxidation of lipid particles in the presence of iron ions. AKanmu D et al showed that the concentration of ergothiogen in the body can act as an antioxidant.

Protective effects against the cells
L-Ergothionein is a powerful secondary chlorine acid scavenger (HOCl), and while many compounds react with secondary chlorine acid, few react as quickly as ergothioneine. A 1-anti-protease inhibitor (API), such as elastase, is particularly sensitive to hypochlorous acid, and the physiological concentration of ergotamine is very effective in protecting API against inactivation caused by hypochlorite, because neutrophils are the main source of hypochlorous acid in the body, one of its role is to protect red blood cells from neutrophils from normal function or pathological inflammation sites.

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